Alan Hruza

Alan Hruza

Central US Merck & Co., Inc. - / United States
Natural Sciences / Biological Science
AD Scientific Index ID: 4376477
person_outline Alan Hruza's MOST POPULAR ARTICLES
1-) Discovery of a novel ERK inhibitor with activity in models of acquired resistance to BRAF and MEK inhibitorsEJ Morris, S Jha, CR Restaino, P Dayananth, H Zhu, A Cooper, D Carr, ...Cancer discovery 3 (7), 742-750, 20136202013
2-) Structural characterization of nitric oxide synthase isoforms reveals striking active-site conservationTO Fischmann, A Hruza, XD Niu, JD Fossetta, CA Lunn, E Dolphin, ...Nature structural biology 6 (3), 233-242, 19995131999
3-) Zinc mediated dimer of human interferon-α2b revealed by X-ray crystallographyR Radhakrishnan, LJ Walter, A Hruza, P Reichert, PP Trotta, ...Structure 4 (12), 1453-1463, 19963381996
4-) Structure of the insulin receptor–insulin complex by single-particle cryo-EM analysisG Scapin, VP Dandey, Z Zhang, W Prosise, A Hruza, T Kelly, T Mayhood, ...Nature 556 (7699), 122-125, 20182332018
5-) Discovery of dinaciclib (SCH 727965): a potent and selective inhibitor of cyclin-dependent kinasesK Paruch, MP Dwyer, C Alvarez, C Brown, TY Chan, RJ Doll, K Keertikar, ...ACS medicinal chemistry letters 1 (5), 204-208, 20101982010