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Andrea Testa
Amphista Therapeutics Ltd. - Solna / United States
Natural Sciences / Biological Science
AD Scientific Index ID: 4979058
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Andrea Testa's MOST POPULAR ARTICLES
1-)
Structural basis of PROTAC cooperative recognition for selective protein degradation MS Gadd, A Testa, X Lucas, KH Chan, W Chen, DJ Lamont, M Zengerle, ... Nature Chemical Biology 13 (5), 514-521, 2017 7022017
2-)
Iterative Design and Optimization of Initially Inactive Proteolysis Targeting Chimeras (PROTACs) Identify VZ185 as a Potent, Fast, and Selective von Hippel–Lindau (VHL) Based … V Zoppi, SJ Hughes, C Maniaci, A Testa, T Gmaschitz, C Wieshofer, ... Journal of medicinal chemistry 62 (2), 699-726, 2018 2092018
3-)
Homo-PROTACs: bivalent small-molecule dimerizers of the VHL E3 ubiquitin ligase to induce self-degradation C Maniaci, SJ Hughes, A Testa, W Chen, DJ Lamont, S Rocha, DR Alessi, ... Nature communications 8 (1), 1-14, 2017 2072017
4-)
Impact of target warhead and linkage vector on inducing protein degradation: comparison of bromodomain and extra-terminal (BET) degraders derived from triazolodiazepine (JQ1 …KH Chan, M Zengerle, A Testa, A CiulliJournal of medicinal chemistry 61 (2), 504-513, 20182312018
5-)
Structure‐Based Design of a Macrocyclic PROTACA Testa, SJ Hughes, X Lucas, JE Wright, A CiulliAngewandte Chemie 132 (4), 1744-1751, 20202042020
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