Ayman El-Kattan

Ayman El-Kattan

Pfizer Inc. - New York / United States
Social Sciences / Transportation Science & Technology
AD Scientific Index ID: 4391696
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person_outline Ayman El-Kattan's MOST POPULAR ARTICLES
1-) Delineating the role of cooperativity in the design of potent PROTACs for BTKA Zorba, C Nguyen, Y Xu, J Starr, K Borzilleri, J Smith, H Zhu, KA Farley, ...Proceedings of the National Academy of Sciences 115 (31), E7285-E7292, 20182842018
2-) Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass eliminationMVS Varma, RS Obach, C Rotter, HR Miller, G Chang, SJ Steyn, ...Journal of medicinal chemistry 53 (3), 1098-1108, 20102742010
3-) Development of a new permeability assay using low‐efflux MDCKII cellsL Di, C Whitney‐Pickett, JP Umland, H Zhang, X Zhang, DF Gebhard, ...Journal of pharmaceutical sciences 100 (11), 4974-4985, 20112432011
4-) Predicting clearance mechanism in drug discovery: extended clearance classification system (ECCS)MV Varma, SJ Steyn, C Allerton, AF El-KattanPharmaceutical research 32, 3785-3802, 20152762015
5-) Mechanistic pharmacokinetic modeling for the prediction of transporter-mediated disposition in humans from sandwich culture human hepatocyte dataHM Jones, HA Barton, Y Lai, Y Bi, E Kimoto, S Kempshall, SC Tate, ...Drug Metabolism and Disposition 40 (5), 1007-1017, 20122652012