Caroline Rynn

Caroline Rynn

Roche - Basel / Switzerland
Medical and Health Sciences / Pharmacy & Pharmaceutical Sciences
AD Scientific Index ID: 4467574
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person_outline Caroline Rynn's MOST POPULAR ARTICLES
1-) Discovery of a dihydroisoquinolinone derivative (NVP-CGM097): a highly potent and selective MDM2 inhibitor undergoing phase 1 clinical trials in p53wt tumorsP Holzer, K Masuya, P Furet, J Kallen, T Valat-Stachyra, S Ferretti, ...Journal of medicinal chemistry 58 (16), 6348-6358, 20152062015
2-) Fundamental aspects of DMPK optimization of targeted protein degradersC Cantrill, P Chaturvedi, C Rynn, JP Schaffland, I Walter, MB WittwerDrug discovery today 25 (6), 969-982, 20201222020
3-) A distinct p53 target gene set predicts for response to the selective p53–HDM2 inhibitor NVP-CGM097S Jeay, S Gaulis, S Ferretti, H Bitter, M Ito, T Valat, M Murakami, S Ruetz, ...Elife 4, e06498, 2015832015
4-) In vitro assessment of colistin\'s antipseudomonal antimicrobial interactions with other antibioticsAP MacGowan, C Rynn, M Wootton, KE Bowker, HA Holt, DS ReevesClinical microbiology and infection 5 (1), 32-36, 1999631999
5-) Membrane transporters: Fundamentals, function and their role in ADMEJ Keogh, B Hagenbuch, C Rynn, B Stieger, G Nicholls252016