Caroline Rynn

Caroline Rynn

Roche - Basel / Switzerland
Medical and Health Sciences / Pharmacy & Pharmaceutical Sciences
AD Scientific Index ID: 4467574
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person_outline Caroline Rynn's MOST POPULAR ARTICLES
1-) Discovery of a dihydroisoquinolinone derivative (NVP-CGM097): a highly potent and selective MDM2 inhibitor undergoing phase 1 clinical trials in p53wt tumors Journal of medicinal chemistry 58 (16), 6348-6358, 2015
2-) Fundamental aspects of DMPK optimization of targeted protein degraders Drug discovery today 25 (6), 969-982, 2020
3-) A distinct p53 target gene set predicts for response to the selective p53–HDM2 inhibitor NVP-CGM097 Elife 4, e06498, 2015
4-) In vitro assessment of colistin's antipseudomonal antimicrobial interactions with other antibiotics Clinical microbiology and infection 5 (1), 32-36, 1999
5-) Membrane transporters: Fundamentals, function and their role in ADME