Charles E Grimshaw

Charles E Grimshaw

Takeda Pharmaceutical Company Limited - Osaka / Japan
Medical and Health Sciences / Biochemistry
AD Scientific Index ID: 4404216
武田薬品工業株式会社
person_outline Charles E Grimshaw's MOST POPULAR ARTICLES
1-) The promise and peril of chemical probesCH Arrowsmith, JE Audia, C Austin, J Baell, J Bennett, J Blagg, C Bountra, ...Nature chemical biology 11 (8), 536-541, 20157062015
2-) Exploration of the HDAC2 foot pocket: Synthesis and SAR of substituted N-(2-aminophenyl) benzamidesJC Bressi, AJ Jennings, R Skene, Y Wu, R Melkus, R De Jong, ...Bioorganic & medicinal chemistry letters 20 (10), 3142-3145, 20102752010
3-) Tyrosine-48 is the proton donor and histidine-110 directs substrate stereochemical selectivity in the reduction reaction of human aldose reductase: enzyme kinetics and crystal …KM Bohren, CE Grimshaw, CJ Lai, DH Harrison, D Ringe, GA Petsko, ...Biochemistry 33 (8), 2021-2032, 19942281994
4-) Stereochemistry of the rearrangement of chorismate to prephenate: chorismate mutase involves a chair transition stateSG Sogo, TS Widlanski, JH Hoare, CE Grimshaw, GA Berchtold, ...Journal of the American Chemical Society 106 (9), 2701-2703, 19841711984
5-) Mechanism of human aldehyde reductase: characterization of the active site pocketOA Barski, KH Gabbay, CE Grimshaw, KM BohrenBiochemistry 34 (35), 11264-11275, 19951621995