Christian Lessard

Christian Lessard

University of Florida - Gainesville / United States
Natural Sciences / Molecular Biology & Genetics
AD Scientific Index ID: 1612980
person_outline Christian Lessard's MOST POPULAR ARTICLES
1-) γ‐Secretase inhibitors in cancer clinical trials are pharmacologically and functionally distinctY Ran, F Hossain, A Pannuti, CB Lessard, GZ Ladd, JI Jung, LM Minter, ...EMBO molecular medicine 9 (7), 950-966, 20171072017
2-) Alzheimer’s disease phospholipase C-gamma-2 (PLCG2) protective variant is a functional hypermorphL Magno, CB Lessard, M Martins, V Lang, P Cruz, Y Asi, M Katan, ...Alzheimer\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\'s research & therapy 11 (1), 1-11, 2019842019
3-) High‐affinity interactions and signal transduction between Aβ oligomers and TREM 2CB Lessard, SL Malnik, Y Zhou, TB Ladd, PE Cruz, Y Ran, TE Mahan, ...EMBO molecular medicine 10 (11), e9027, 2018972018
4-) The overexpression of presenilin2 and Alzheimer\'s-disease-linked presenilin2 variants influences TRPC6-enhanced Ca2+ entry into HEK293 cellsCB Lessard, MP Lussier, S Cayouette, G Bourque, G BoulayCellular signalling 17 (4), 437-445, 2005922005
5-) Substrate sequence influences γ-secretase modulator activity, role of the transmembrane domain of the amyloid precursor proteinSA Sagi, CB Lessard, KD Winden, H Maruyama, JC Koo, S Weggen, ...Journal of Biological Chemistry 286 (46), 39794-39803, 2011432011