Christian Wiesmann

Christian Wiesmann

Novartis Institutes for BioMedical Research - Bhubaneswar / United States
Natural Sciences / Biological Science
AD Scientific Index ID: 4393035
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person_outline Christian Wiesmann's MOST POPULAR ARTICLES
1-) De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-κB signallingIE Wertz, KM O\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\'rourke, H Zhou, M Eby, L Aravind, S Seshagiri, P Wu, ...Nature 430 (7000), 694-699, 200420262004
2-) Selection and analysis of an optimized anti-VEGF antibody: crystal structure of an affinity-matured Fab in complex with antigenY Chen, C Wiesmann, G Fuh, B Li, HW Christinger, P McKay, AM de Vos, ...Journal of molecular biology 293 (4), 865-881, 199910251999
3-) The Identification of 2-(1H-Indazol-4-yl)-6-(4-methanesulfonyl-piperazin-1-ylmethyl)-4-morpholin-4-yl-thieno[3,2-d]pyrimidine (GDC-0941) as a Potent, Selective …AJ Folkes, K Ahmadi, WK Alderton, S Alix, SJ Baker, G Box, ...Journal of medicinal chemistry 51 (18), 5522-5532, 20087942008
4-) Crystal structure at 1.7 Å resolution of VEGF in complex with domain 2 of the Flt-1 receptorC Wiesmann, G Fuh, HW Christinger, C Eigenbrot, JA Wells, AM de VosCell 91 (5), 695-704, 19976911997
5-) Allosteric inhibition of protein tyrosine phosphatase 1BC Wiesmann, KJ Barr, J Kung, J Zhu, DA Erlanson, W Shen, BJ Fahr, ...Nature structural & molecular biology 11 (8), 730-737, 20045802004