Dan Xia

Dan Xia

Harvard University - Cambridge / United States
Medical and Health Sciences / Neuroscience
AD Scientific Index ID: 1411926
person_outline Dan Xia's MOST POPULAR ARTICLES
1-) TREM2 regulates microglial cholesterol metabolism upon chronic phagocytic challengeAA Nugent, K Lin, B Van Lengerich, S Lianoglou, L Przybyla, SS Davis, ...Neuron 105 (5), 837-854. e9, 20202372020
2-) Presenilin-1 knockin mice reveal loss-of-function mechanism for familial Alzheimer’s diseaseD Xia, H Watanabe, B Wu, SH Lee, Y Li, E Tsvetkov, VY Bolshakov, ...Neuron 85 (5), 967-981, 20152262015
3-) Enhancing protective microglial activities with a dual function TREM 2 antibody to the stalk regionK Schlepckow, KM Monroe, G Kleinberger, L Cantuti‐Castelvetri, ...EMBO molecular medicine 12 (4), e11227, 20201082020
4-) A TREM2-activating antibody with a blood–brain barrier transport vehicle enhances microglial metabolism in Alzheimer’s disease modelsB van Lengerich, L Zhan, D Xia, D Chan, D Joy, JI Park, D Tatarakis, ...Nature neuroscience 26 (3), 416-429, 20231482023
5-) Novel App knock-in mouse model shows key features of amyloid pathology and reveals profound metabolic dysregulation of microgliaD Xia, S Lianoglou, T Sandmann, M Calvert, JH Suh, E Thomsen, ...Molecular Neurodegeneration 17 (1), 41, 2022752022