David Ian Fisher

David Ian Fisher

AstraZeneca, Sweden - Södertälje / Sweden
Natural Sciences / Biological Science
AD Scientific Index ID: 4453440
-
person_outline David Ian Fisher's MOST POPULAR ARTICLES
1-) Structures of closed and open conformations of dimeric human ATM Science advances 3 (5), e1700933, 2017
2-) Discovery of AZD9833, a potent and orally bioavailable selective estrogen receptor degrader and antagonist Journal of medicinal chemistry 63 (23), 14530-14559, 2020
3-) Nudix hydrolases that degrade dinucleoside and diphosphoinositol polyphosphates also have 5-phosphoribosyl 1-pyrophosphate (PRPP) pyrophosphatase activity that generates the … Journal of Biological Chemistry 277 (49), 47313-47317, 2002
4-) Systematic evaluation of CRISPRa and CRISPRi modalities enables development of a multiplexed, orthogonal gene activation and repression system ACS Synthetic Biology 8 (9), 1998-2006, 2019
5-) The Next-Generation Oral Selective Estrogen Receptor Degrader Camizestrant (AZD9833) Suppresses ER+ Breast Cancer Growth and Overcomes Endocrine and … Cancer research 83 (23), 3989-4004, 2023