David Ruddy

David Ruddy

Novartis Institutes for BioMedical Research - Bhubaneswar / United States
Natural Sciences / Molecular Biology & Genetics
AD Scientific Index ID: 4394108
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person_outline David Ruddy's MOST POPULAR ARTICLES
1-) A novel MHC class I–like gene is mutated in patients with hereditary haemochromatosisJN Feder, A Gnirke, W Thomas, Z Tsuchihashi, DA Ruddy, A Basava, ...Nature genetics 13 (4), 399-408, 199644611996
2-) High-throughput screening using patient-derived tumor xenografts to predict clinical trial drug responseH Gao, JM Korn, S Ferretti, JE Monahan, Y Wang, M Singh, C Zhang, ...Nature medicine 21 (11), 1318-1325, 201510932015
3-) aph-1 and pen-2 are required for Notch pathway signaling, γ-secretase cleavage of βAPP, and presenilin protein accumulationR Francis, G McGrath, J Zhang, DA Ruddy, M Sym, J Apfeld, M Nicoll, ...Developmental cell 3 (1), 85-97, 200210902002
4-) Tumor cells can follow distinct evolutionary paths to become resistant to epidermal growth factor receptor inhibitionAN Hata, MJ Niederst, HL Archibald, M Gomez-Caraballo, FM Siddiqui, ...Nature medicine 22 (3), 262-269, 201610032016
5-) Project DRIVE: a compendium of cancer dependencies and synthetic lethal relationships uncovered by large-scale, deep RNAi screeningER McDonald, A De Weck, MR Schlabach, E Billy, KJ Mavrakis, ...Cell 170 (3), 577-592. e10, 20176772017