Denzil Bernard

Denzil Bernard

Atomwise Inc. - San Francisco / United States
Others
AD Scientific Index ID: 4979269
person_outline Denzil Bernard's MOST POPULAR ARTICLES
1-) Temporal activation of p53 by a specific MDM2 inhibitor is selectively toxic to tumors and leads to complete tumor growth inhibition S Shangary, D Qin, D McEachern, M Liu, RS Miller, S Qiu, ... Proceedings of the National Academy of Sciences 105 (10), 3933-3938, 2008 7892008
2-) Small-molecule inhibitors of the MDM2–p53 protein–protein interaction (MDM2 Inhibitors) in clinical trials for cancer treatment: miniperspective Y Zhao, A Aguilar, D Bernard, S Wang Journal of medicinal chemistry 58 (3), 1038-1052, 2015 4772015
3-) SAR405838: an optimized inhibitor of MDM2–p53 interaction that induces complete and durable tumor regression S Wang, W Sun, Y Zhao, D McEachern, I Meaux, C Barrière, JA Stuckey, ... Cancer research 74 (20), 5855-5865, 2014 2902014
4-) A potent small-molecule inhibitor of the MDM2–p53 interaction (MI-888) achieved complete and durable tumor regression in miceY Zhao, S Yu, W Sun, L Liu, J Lu, D McEachern, S Shargary, D Bernard, ...Journal of medicinal chemistry 56 (13), 5553-5561, 20132952013
5-) Targeting the MDM2–p53 protein–protein interaction for new cancer therapy: progress and challengesS Wang, Y Zhao, A Aguilar, D Bernard, CY YangCold Spring Harbor perspectives in medicine 7 (5), a026245, 20172732017