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Donald M O Rourke
AD Scientific Index 2024
Natural Sciences / Molecular Biology & Genetics
University of Pennsylvania - Philadelphia / United States
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Donald M O Rourke's MOST POPULAR ARTICLES
1-)
IDH mutation impairs histone demethylation and results in a block to cell differentiationC Lu, PS Ward, GS Kapoor, D Rohle, S Turcan, O Abdel-Wahab, ...Nature 483 (7390), 474-478, 201218842012
2-)
A single dose of peripherally infused EGFRvIII-directed CAR T cells mediates antigen loss and induces adaptive resistance in patients with recurrent glioblastomaDM O’Rourke, MLP Nasrallah, A Desai, JJ Melenhorst, K Mansfield, ...Science translational medicine 9 (399), eaaa0984, 201710992017
3-)
Rindopepimut with temozolomide for patients with newly diagnosed, EGFRvIII-expressing glioblastoma (ACT IV): a randomised, double-blind, international phase 3 trialM Weller, N Butowski, DD Tran, LD Recht, M Lim, H Hirte, L Ashby, ...The Lancet Oncology 18 (10), 1373-1385, 20177112017
4-)
A patient-derived glioblastoma organoid model and biobank recapitulates inter-and intra-tumoral heterogeneityF Jacob, RD Salinas, DY Zhang, PTT Nguyen, JG Schnoll, SZH Wong, ...Cell 180 (1), 188-204. e22, 20206772020
5-)
Epidermal growth factor receptor transcriptionally up-regulates vascular endothelial growth factor expression in human glioblastoma cells via a pathway involving …A Maity, N Pore, J Lee, D Solomon, DM O’RourkeCancer research 60 (20), 5879-5886, 20003522000
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