Eric Therrien

Schrodinger LLC - - / United States

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AD Scientific Index ID: 4522959

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Eric Therrien's MOST POPULAR ARTICLES

1-) An allosteric mechanism for potent inhibition of human ATP-citrate lyaseJ Wei, S Leit, J Kuai, E Therrien, S Rafi, HJ Harwood Jr, B DeLaBarre, ...Nature 568 (7753), 566-570, 20191092019

2-) Synthesis of functionally diverse bicyclic sulfonamides as constrained proline analogues and application to the design of potential thrombin inhibitorsS Hanessian, H Sailes, E TherrienTetrahedron 59 (35), 7047-7056, 20031082003

3-) N-Benzyl-1-heteroaryl-3-(trifluoromethyl)-1H-pyrazole-5-carboxamides as inhibitors of co-activator associated arginine methyltransferase 1 (CARM1)M Allan, S Manku, E Therrien, N Nguyen, S Styhler, MF Robert, AC Goulet, ...Bioorganic & medicinal chemistry letters 19 (4), 1218-1223, 2009942009

4-) Structure-based design, synthesis, and memapsin 2 (BACE) inhibitory activity of carbocyclic and heterocyclic peptidomimeticsS Hanessian, H Yun, Y Hou, G Yang, M Bayrakdarian, E Therrien, ...Journal of medicinal chemistry 48 (16), 5175-5190, 2005972005

5-) A method for induced-fit docking, scoring, and ranking of flexible ligands. Application to peptidic and pseudopeptidic β-secretase (BACE 1) inhibitorsN Moitessier, E Therrien, S HanessianJournal of medicinal chemistry 49 (20), 5885-5894, 2006902006

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