Eva Hyde

Eva Hyde

University of Birmingham - Birmingham / United Kingdom
Natural Sciences / Biological Science
AD Scientific Index ID: 4322183
person_outline Eva Hyde's MOST POPULAR ARTICLES
1-) Structural and mechanistic studies of Escherichia coli nitroreductase with the antibiotic nitrofurazone: reversed binding orientations in different redox states of the enzymePR Race, AL Lovering, RM Green, A Ossor, SA White, PF Searle, ...Journal of Biological Chemistry 280 (14), 13256-13264, 20052142005
2-) Nitroreductase: a prodrug-activating enzyme for cancer gene therapy.PF Searle, MJ Chen, L Hu, PR Race, AL Lovering, JI Grove, C Guise, ...Clinical & Experimental Pharmacology & Physiology 31 (11), 20041422004
3-) The structure of Escherichia coli nitroreductase complexed with nicotinic acid: three crystal forms at 1.7 Å, 1.8 Å and 2.4 Å resolutionAL Lovering, EI Hyde, PF Searle, SA WhiteJournal of molecular biology 309 (1), 203-213, 20011302001
4-) Kinetic and structural characterisation of Escherichia coli nitroreductase mutants showing improved efficacy for the prodrug substrate CB1954PR Race, AL Lovering, SA White, JI Grove, PF Searle, CW Wrighton, ...Journal of molecular biology 368 (2), 481-492, 20071002007
5-) Generation of Escherichia Coli Nitroreductase Mutants Conferring Improved Cell Sensitization to the Prodrug CB1954JI Grove, AL Lovering, C Guise, PR Race, CJ Wrighton, SA White, EI Hyde, ...Cancer research 63 (17), 5532-5537, 2003962003