Gergana Popova

Gergana Popova

Uppsala University - Uppsala / Sweden
Medical and Health Sciences / Pharmacy & Pharmaceutical Sciences
AD Scientific Index ID: 5482051
Uppsala Universitet
person_outline Gergana Popova's MOST POPULAR ARTICLES
1-) A DHODH inhibitor increases p53 synthesis and enhances tumor cell killing by p53 degradation blockageMJGW Ladds, IMM Van Leeuwen, CJ Drummond, S Chu, AR Healy, ...Nature communications 9 (1), 1107, 2018952018
2-) Lipids shape the electron acceptor-binding site of the peripheral membrane protein dihydroorotate dehydrogenaseJ Costeira-Paulo, J Gault, G Popova, MJGW Ladds, IMM van Leeuwen, ...Cell chemical biology 25 (3), 309-317. e4, 2018282018
3-) Optimization of tetrahydroindazoles as inhibitors of human dihydroorotate dehydrogenase and evaluation of their activity and in vitro metabolic stabilityG Popova, MJGW Ladds, L Johansson, A Saleh, J Larsson, L Sandberg, ...Journal of Medicinal Chemistry 63 (8), 3915-3934, 2020172020
4-) Exploitation of dihydroorotate dehydrogenase (DHODH) and p53 activation as therapeutic targets: A case study in polypharmacologyMJGW Ladds, G Popova, A Pastor-Fernández, S Kannan, ...Journal of Biological Chemistry 295 (52), 17935-17949, 2020142020
5-) Autophagic flux blockage by accumulation of weakly basic tenovins leads to elimination of B-Raf mutant tumour cells that survive vemurafenibMJGW Ladds, A Pastor-Fernandez, G Popova, IMM van Leeuwen, ...Plos one 13 (4), e0195956, 201852018