Greg Delgoffe

Greg Delgoffe

University of Pittsburgh - Pittsburgh / United States
Medical and Health Sciences / Immunology
AD Scientific Index ID: 1618190
person_outline Greg Delgoffe's MOST POPULAR ARTICLES
1-) The mTOR kinase differentially regulates effector and regulatory T cell lineage commitmentGM Delgoffe, TP Kole, Y Zheng, PE Zarek, KL Matthews, B Xiao, ...Immunity 30 (6), 832-844, 200912382009
2-) The kinase mTOR regulates the differentiation of helper T cells through the selective activation of signaling by mTORC1 and mTORC2GM Delgoffe, KN Pollizzi, AT Waickman, E Heikamp, DJ Meyers, ...Nature immunology 12 (4), 295-303, 201110832011
3-) The tumor microenvironment represses T cell mitochondrial biogenesis to drive intratumoral T cell metabolic insufficiency and dysfunctionNE Scharping, AV Menk, RS Moreci, RD Whetstone, RE Dadey, ...Immunity 45 (2), 374-388, 20165752016
4-) Bioenergetic insufficiencies due to metabolic alterations regulated by the inhibitory receptor PD-1 are an early driver of CD8+ T cell exhaustionB Bengsch, AL Johnson, M Kurachi, PM Odorizzi, KE Pauken, J Attanasio, ...immunity 45 (2), 358-373, 20167592016
5-) Metabolic support of tumour-infiltrating regulatory T cells by lactic acidMLJ Watson, PDA Vignali, SJ Mullett, AE Overacre-Delgoffe, RM Peralta, ...Nature 591 (7851), 645-651, 20217272021