Holdgate Ga

AstraZeneca, Sweden - Södertälje / Sweden

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AD Scientific Index ID: 4400149

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Holdgate Ga's MOST POPULAR ARTICLES

1-) Preclinical and clinical pharmacology of Rosuvastatin, a new 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitorF McTaggart, L Buckett, R Davidson, G Holdgate, A McCormick, ...The American journal of cardiology 87 (5), 28-32, 20015492001

2-) Epidermal growth factor receptor tyrosine kinase: Investigation of catalytic mechanism, structure-based searching and discovery of a potent inhibitorWHJ Ward, PN Cook, AM Slater, DH Davies, GA HoldgateBiochemical pharmacology 48 (4), 659-666, 19943161994

3-) Measurements of binding thermodynamics in drug discoveryGA Holdgate, WHJ WardDrug discovery today 10 (22), 1543-1550, 20052662005

4-) The entropic penalty of ordered water accounts for weaker binding of the antibiotic novobiocin to a resistant mutant of DNA gyrase: a thermodynamic and crystallographic studyGA Holdgate, A Tunnicliffe, WHJ Ward, SA Weston, G Rosenbrock, ...Biochemistry 36 (32), 9663-9673, 19972761997

5-) Preclinical anticancer activity of the potent, oral Src inhibitor AZD0530TP Green, M Fennell, R Whittaker, J Curwen, V Jacobs, J Allen, A Logie, ...Molecular oncology 3 (3), 248-261, 20092532009

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