Irene Scarfã2

Harvard University - Cambridge / United States

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AD Scientific Index ID: 1405108

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Irene Scarfã2's MOST POPULAR ARTICLES

1-) Engineered CRISPR–Cas12a variants with increased activities and improved targeting ranges for gene, epigenetic and base editingBP Kleinstiver, AA Sousa, RT Walton, YE Tak, JY Hsu, K Clement, ...Nature Biotechnology, 1, 20193482019

2-) CAR-T cells secreting BiTEs circumvent antigen escape without detectable toxicityBD Choi, X Yu, AP Castano, AA Bouffard, A Schmidts, RC Larson, ...Nature biotechnology, 1, 20192782019

3-) CRISPR-Cas9 disruption of PD-1 enhances activity of universal EGFRvIII CAR T cells in a preclinical model of human glioblastomaBD Choi, X Yu, AP Castano, H Darr, DB Henderson, AA Bouffard, ...Journal for ImmunoTherapy of Cancer 7 (1), 1-8, 20191712019

4-) CAR T cell killing requires the IFNγR pathway in solid but not liquid tumoursRC Larson, MC Kann, SR Bailey, NJ Haradhvala, PM Llopis, AA Bouffard, ...Nature 604 (7906), 563-570, 20222692022

5-) Reversible ON-and OFF-switch chimeric antigen receptors controlled by lenalidomideM Jan, I Scarfò, RC Larson, A Walker, A Schmidts, AA Guirguis, JA Gasser, ...Science Translational Medicine 13 (575), 20212192021

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