Jacob D Aguirre

Jacob D Aguirre

Brescia University College - Ontario / Canada
Natural Sciences / Biological Science
AD Scientific Index ID: 794395
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person_outline Jacob D Aguirre's MOST POPULAR ARTICLES
1-) Disruption of the autoinhibited state primes the E3 ligase parkin for activation and catalysis The EMBO journal 34 (20), 2506-2521, 2015
2-) A molecular explanation for the recessive nature of parkin-linked Parkinson’s disease Nature communications 4, 1983, 2013
3-) Structure of phosphorylated UBL domain and insights into PINK1-orchestrated parkin activation Proceedings of the National Academy of Sciences 114 (2), 298-303, 2017
4-) Structural Basis of BRCC36 Function in DNA Repair and Immune Regulation Molecular Cell, 2019
5-) Synergistic recruitment of UbcH7~ Ub and phosphorylated Ubl domain triggers parkin activation The EMBO journal 37 (23), e100014, 2018