Jacob S Roth

Jacob S Roth

Albert Einstein College of Medicine - Bronx / United States
Natural Sciences / Molecular Biology & Genetics
AD Scientific Index ID: 806895
AECOM
person_outline Jacob S Roth's MOST POPULAR ARTICLES
1-) Remdesivir: a review of its discovery and development leading to emergency use authorization for treatment of COVID-19RT Eastman, JS Roth, KR Brimacombe, A Simeonov, M Shen, S Patnaik, ...ACS central Science 6 (5), 672-683, 20206782020
2-) A widely-applicable high-throughput cellular thermal shift assay (CETSA) using split Nano LuciferaseNJ Martinez, RR Asawa, MG Cyr, A Zakharov, DJ Urban, JS Roth, ...Scientific reports 8 (1), 1-16, 2018622018
3-) Discovery of orally bioavailable, quinoline-based aldehyde dehydrogenase 1A1 (ALDH1A1) inhibitors with potent cellular activitySM Yang, NJ Martinez, A Yasgar, C Danchik, C Johansson, Y Wang, ...Journal of medicinal chemistry 61 (11), 4883-4903, 2018562018
4-) Canvass: A Crowd-Sourced, Natural-Product Screening Library for Exploring Biological SpaceSE Kearney, G Zahoránszky-Kőhalmi, KR Brimacombe, MJ Henderson, ...ACS central science 4 (12), 1727-1741, 2018422018
5-) PRC2 Inhibitors Overcome Glucocorticoid Resistance Driven by NSD2 Mutation in Pediatric Acute Lymphoblastic LeukemiaJ Li, J Hlavka-Zhang, JH Shrimp, C Piper, D Dupéré-Richér, JS Roth, ...Cancer Discovery 12 (1), 186-203, 2022322022