Jean Dam

Jean Dam

University of Cape Town - Cape Town / South Africa
Natural Sciences / Chemical Sciences
AD Scientific Index ID: 4642986
Universiteit van Kaapstad
person_outline Jean Dam's MOST POPULAR ARTICLES
1-) Synthesis of copper and zinc 2-(pyridin-2-yl) imidazo [1, 2-a] pyridine complexes and their potential anticancer activityJ Dam, Z Ismail, T Kurebwa, N Gangat, L Harmse, HM Marques, ...European journal of medicinal chemistry 126, 353-368, 2017532017
2-) Identification and profiling of a novel diazaspiro [3.4] octane chemical series active against multiple stages of the human malaria parasite Plasmodium falciparum and …C Le Manach, J Dam, JG Woodland, G Kaur, LP Khonde, C Brunschwig, ...Journal of Medicinal Chemistry 64 (4), 2291-2309, 2021122021
3-) Copper-imidazo[1,2-a]pyridines induce intrinsic apoptosis and modulate the expression of mutated p53, haem-oxygenase-1 and apoptotic inhibitory proteins in HT …L Harmse, N Gangat, C Martins-Furness, J Dam, CB de KoningApoptosis 24 (7-8), 623-643, 2019162019
4-) Identification of 2, 4-Disubstituted Imidazopyridines as Hemozoin Formation Inhibitors with Fast-Killing Kinetics and In Vivo Efficacy in the Plasmodium falciparum NSG Mouse ModelA Horatscheck, A Andrijevic, AT Nchinda, C Le Manach, T Paquet, ...Journal of Medicinal Chemistry 63 (21), 13013-13030, 2020152020
5-) Copper-imidazo [1, 2-a] pyridines differentially modulate pro-and anti-apoptotic protein and gene expression in HL-60 and K562 leukaemic cells to cause apoptotic cell deathZ Ismail, J Dam, C Penny, CB de Koning, L HarmseBiochimica et Biophysica Acta (BBA)-Molecular Cell Research 1869 (1), 119160, 2022102022