Jeffrey Axten

Jeffrey Axten

GlaxoSmithKline - Needham / United Kingdom
Natural Sciences / Chemical Sciences
AD Scientific Index ID: 4370690
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person_outline Jeffrey Axten's MOST POPULAR ARTICLES
1-) Oral treatment targeting the unfolded protein response prevents neurodegeneration and clinical disease in prion-infected mice Science translational medicine 5 (206), 206ra138-206ra138, 2013
2-) Characterization of a novel PERK kinase inhibitor with antitumor and antiangiogenic activity Cancer research 73 (6), 1993-2002, 2013
3-) Pharmacological targeting of the unfolded protein response for disease intervention Nature chemical biology 15 (8), 764-775, 2019
4-) Discovery of GSK2656157: an optimized PERK inhibitor selected for preclinical development ACS medicinal chemistry letters 4 (10), 964-968, 2013
5-) Pharmacological targeting of the unfolded protein response for disease interventionC Hetz, JM Axten, JB PattersonNature chemical biology 15 (8), 764-775, 20192492019