Jianzhong Hu

Jianzhong Hu

St. Jude Children's Research Hospital - Memphis / United States
Medical and Health Sciences / Pharmacology
AD Scientific Index ID: 5698329
person_outline Jianzhong Hu's MOST POPULAR ARTICLES
1-) Network-based systems pharmacology reveals heterogeneity in LCK and BCL2 signaling and therapeutic sensitivity of T-cell acute lymphoblastic leukemia Nature cancer 2 (3), 284-299, 2021
2-) Preclinical evaluation of proteolytic targeting of LCK as a therapeutic approach in T cell acute lymphoblastic leukemia Science translational medicine 14 (659), eabo5228, 2022
3-) Interrogating bromodomain inhibitor resistance in KMT2A-rearranged leukemia through combinatorial CRISPR screens Proceedings of the National Academy of Sciences 120 (16), e2220134120, 2023
4-) Preclinical pharmacokinetic and pharmacodynamic evaluation of dasatinib and ponatinib for the treatment of T-cell acute lymphoblastic leukemia Leukemia 37 (6), 1194-1203, 2023
5-) A multiomic atlas identifies a treatment-resistant, bone marrow progenitor-like cell population in T cell acute lymphoblastic leukemia Nature cancer 6 (1), 102-122, 2025