Joanne (Hulett) Hildebrand

Joanne (Hulett) Hildebrand

Walter and Eliza Hall Institute of Medical Research - Parkville / Australia
Others
AD Scientific Index ID: 4398228
person_outline Joanne (Hulett) Hildebrand's MOST POPULAR ARTICLES
1-) The pseudokinase MLKL mediates necroptosis via a molecular switch mechanismJM Murphy, PE Czabotar, JM Hildebrand, IS Lucet, JG Zhang, ...Immunity 39 (3), 443-453, 20139642013
2-) Activation of the pseudokinase MLKL unleashes the four-helix bundle domain to induce membrane localization and necroptotic cell deathJM Hildebrand, MC Tanzer, IS Lucet, SN Young, SK Spall, P Sharma, ...Proceedings of the National Academy of Sciences 111 (42), 15072-15077, 20144662014
3-) MLKL trafficking and accumulation at the plasma membrane control the kinetics and threshold for necroptosisAL Samson, Y Zhang, ND Geoghegan, XJ Gavin, KA Davies, ...Nature communications 11 (1), 3151, 20201692020
4-) Conformational switching of the pseudokinase domain promotes human MLKL tetramerization and cell death by necroptosisEJ Petrie, JJ Sandow, AV Jacobsen, BJ Smith, MDW Griffin, IS Lucet, ...Nature communications 9 (1), 2422, 20181862018
5-) EspL is a bacterial cysteine protease effector that cleaves RHIM proteins to block necroptosis and inflammationJS Pearson, C Giogha, S Mühlen, U Nachbur, CLL Pham, Y Zhang, ...Nature microbiology 2 (4), 1-10, 20171842017