Joseph A Fraietta

Joseph A Fraietta

University of Pennsylvania - Philadelphia / United States
Natural Sciences / Molecular Biology & Genetics
AD Scientific Index ID: 1547144
person_outline Joseph A Fraietta's MOST POPULAR ARTICLES
1-) Determinants of response and resistance to CD19 chimeric antigen receptor (CAR) T cell therapy of chronic lymphocytic leukemiaJA Fraietta, SF Lacey, EJ Orlando, I Pruteanu-Malinici, M Gohil, S Lundh, ...Nature medicine 24 (5), 563-571, 20189212018
2-) CRISPR-engineered T cells in patients with refractory cancerEA Stadtmauer, JA Fraietta, MM Davis, AD Cohen, KL Weber, E Lancaster, ...Science 367 (6481), eaba7365, 20209412020
3-) Distinct signaling of coreceptors regulates specific metabolism pathways and impacts memory development in CAR T cellsOU Kawalekar, RS O’Connor, JA Fraietta, L Guo, SE McGettigan, ...Immunity 44 (2), 380-390, 20169402016
4-) Disruption of TET2 promotes the therapeutic efficacy of CD19-targeted T cellsJA Fraietta, CL Nobles, MA Sammons, S Lundh, SA Carty, TJ Reich, ...Nature 558 (7709), 307-312, 20187692018
5-) Decade-long leukaemia remissions with persistence of CD4+ CAR T cellsJJ Melenhorst, GM Chen, M Wang, DL Porter, C Chen, MKA Collins, ...Nature 602 (7897), 503-509, 20226222022