Joseph Alan Ware

Joseph Alan Ware

Seagen - Bothell / United States
Medical and Health Sciences / Pharmacy & Pharmaceutical Sciences
AD Scientific Index ID: 4970935
person_outline Joseph Alan Ware's MOST POPULAR ARTICLES
1-) Membrane transporters in drug development KM Giacomini, SM Huang, DJ Tweedie, LZ Benet, KLR Brouwer, X Chu, ... Nature reviews Drug discovery 9 (3), 215-236, 2010 3195*2010
2-) Drug absorption interactions between oral targeted anticancer agents and PPIs: is pH‐dependent solubility the Achilles heel of targeted therapy? NR Budha, A Frymoyer, GS Smelick, JY Jin, MR Yago, MJ Dresser, ... Clinical Pharmacology & Therapeutics 92 (2), 203-213, 2012 3192012
3-) First-in-human phase I study of pictilisib (GDC-0941), a potent pan–class I phosphatidylinositol-3-kinase (PI3K) inhibitor, in patients with advanced solid tumorsD Sarker, JE Ang, R Baird, R Kristeleit, K Shah, V Moreno, PA Clarke, ...Clinical cancer research 21 (1), 77-86, 20152912015
4-) Drug–drug interactions mediated through P-glycoprotein: clinical relevance and in vitro–in vivo correlation using digoxin as a probe drugKS Fenner, MD Troutman, S Kempshall, JA Cook, JA Ware, DA Smith, ...Clinical Pharmacology & Therapeutics 85 (2), 173-181, 20083122008
5-) Discovery of a potent small-molecule antagonist of inhibitor of apoptosis (IAP) proteins and clinical candidate for the treatment of cancer (GDC-0152)JA Flygare, M Beresini, N Budha, H Chan, IT Chan, S Cheeti, F Cohen, ...Journal of medicinal chemistry 55 (9), 4101-4113, 20122752012