Kyle Konze

Kyle Konze

Schrodinger LLC - - / United States
Medical and Health Sciences / Pharmacy & Pharmaceutical Sciences
AD Scientific Index ID: 4523463
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person_outline Kyle Konze's MOST POPULAR ARTICLES
1-) An orally bioavailable chemical probe of the lysine methyltransferases EZH2 and EZH1KD Konze, A Ma, F Li, D Barsyte-Lovejoy, T Parton, CJ MacNevin, F Liu, ...ACS chemical biology 8 (6), 1324-1334, 20134912013
2-) Selective inhibition of EZH2 and EZH1 enzymatic activity by a small molecule suppresses MLL-rearranged leukemiaB Xu, DM On, A Ma, T Parton, KD Konze, SG Pattenden, DF Allison, L Cai, ...Blood, The Journal of the American Society of Hematology 125 (2), 346-357, 20152432015
3-) Selective inhibitors of protein methyltransferasesHU Kaniskan, KD Konze, J JinJournal of medicinal chemistry 58 (4), 1596-1629, 20151382015
4-) Targeting EZH2 and PRC2 dependence as novel anticancer therapyB Xu, KD Konze, J Jin, GG WangExperimental hematology 43 (8), 698-712, 20151272015
5-) Reaction-Based Enumeration, Active Learning, and Free Energy Calculations To Rapidly Explore Synthetically Tractable Chemical Space and Optimize Potency of Cyclin-Dependent …KD Konze, PH Bos, MK Dahlgren, K Leswing, I Tubert-Brohman, ...Journal of chemical information and modeling 59 (9), 3782-3793, 20191222019