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Lisa (Hooker) O'Fee
Institute of Cancer Research University of London - London / United Kingdom
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AD Scientific Index ID: 5984375
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Lisa (Hooker) O'Fee's MOST POPULAR ARTICLES
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Discovery of a chemical probe bisamide (CCT251236): an orally bioavailable efficacious pirin ligand from a heat shock transcription factor 1 (HSF1) phenotypic screenMD Cheeseman, NEA Chessum, CS Rye, AE Pasqua, MJ Tucker, ...Journal of medicinal chemistry 60 (1), 180-201, 2017542017
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Rapid Discovery of Pyrido[3,4-d]pyrimidine Inhibitors of Monopolar Spindle Kinase 1 (MPS1) Using a Structure-Based Hybridization ApproachP Innocenti, HL Woodward, S Solanki, S Naud, IM Westwood, N Cronin, ...Journal of medicinal chemistry 59 (8), 3671-3688, 2016352016
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Quantitative analysis of influenza virus RNP interaction with RNA cap structures and comparison to human cap binding protein eIF4EL Hooker, R Sully, B Handa, N Ono, H Koyano, K KlumppBiochemistry 42 (20), 6234-6240, 2003332003
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Introduction of a Methyl Group Curbs Metabolism of Pyrido [3, 4-d] pyrimidine Monopolar Spindle 1 (MPS1) Inhibitors and Enables the Discovery of the Phase 1 Clinical Candidate …HL Woodward, P Innocenti, KMJ Cheung, A Hayes, J Roberts, AT Henley, ...Journal of Medicinal Chemistry 61 (18), 8226-8240, 2018312018
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Characterisation of CCT271850, a selective, oral and potent MPS1 inhibitor, used to directly measure in vivo MPS1 inhibition vs therapeutic efficacyA Faisal, GWY Mak, MD Gurden, CPR Xavier, SJ Anderhub, P Innocenti, ...British journal of cancer 116 (9), 1166-1176, 2017282017
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