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Lixin Wan
AD Scientific Index 2024
Natural Sciences / Molecular Biology & Genetics
H. Lee Moffitt Cancer Center & Research Institute - / United States
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Lixin Wan's MOST POPULAR ARTICLES
1-)
SCFFBW7 regulates cellular apoptosis by targeting MCL1 for ubiquitylation and destructionH Inuzuka, S Shaik, I Onoyama, D Gao, A Tseng, RS Maser, B Zhai, ...Nature 471 (7336), 104-109, 20116552011
2-)
Cell-cycle-regulated activation of Akt kinase by phosphorylation at its carboxyl terminusP Liu, M Begley, W Michowski, H Inuzuka, M Ginzberg, D Gao, P Tsou, ...Nature 508 (7497), 541-545, 20143492014
3-)
Cancer-associated PTEN mutants act in a dominant-negative manner to suppress PTEN protein functionA Papa, L Wan, M Bonora, L Salmena, MS Song, RM Hobbs, A Lunardi, ...Cell 157 (3), 595-610, 20142802014
4-)
Sin1 phosphorylation impairs mTORC2 complex integrity and inhibits downstream Akt signalling to suppress tumorigenesisP Liu, W Gan, H Inuzuka, AS Lazorchak, D Gao, O Arojo, D Liu, L Wan, ...Nature cell biology 15 (11), 1340-1350, 20132962013
5-)
mTOR drives its own activation via SCFβTrCP-dependent degradation of the mTOR inhibitor DEPTORD Gao, H Inuzuka, MKM Tan, H Fukushima, JW Locasale, P Liu, L Wan, ...Molecular cell 44 (2), 290-303, 20112732011
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