Michael Koehler

Michael Koehler

Genentech, Inc - / United States
Medical and Health Sciences / Pharmacy & Pharmaceutical Sciences
AD Scientific Index ID: 4380826
person_outline Michael Koehler's MOST POPULAR ARTICLES
1-) GDC-0449—a potent inhibitor of the hedgehog pathway Bioorganic & medicinal chemistry letters 19 (19), 5576-5581, 2009
2-) Optimized arylomycins are a new class of Gram-negative antibiotics Nature 561 (7722), 189-194, 2018
3-) Discovery of a Potent and Selective BCL-XL Inhibitor with in Vivo Activity ACS medicinal chemistry letters 5 (10), 1088-1093, 2014
4-) The Erbin PDZ Domain Binds with High Affinity and Specificity to the Carboxyl Termini of δ-Catenin and ARVCF∗ Journal of Biological Chemistry 277 (15), 12906-12914, 2002
5-) Origins of PDZ domain ligand specificity: structure determination and mutagenesis of the Erbin PDZ domain Journal of Biological Chemistry 278 (9), 7645-7654, 2003