Michael Koehler

Michael Koehler

Genentech, Inc - South San Francisco / United States
Medical and Health Sciences / Pharmacy & Pharmaceutical Sciences
AD Scientific Index ID: 4380826
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person_outline Michael Koehler's MOST POPULAR ARTICLES
1-) GDC-0449—A potent inhibitor of the hedgehog pathwayKD Robarge, SA Brunton, GM Castanedo, Y Cui, MS Dina, R Goldsmith, ...Bioorganic & medicinal chemistry letters 19 (19), 5576-5581, 20094352009
2-) Optimized arylomycins are a new class of Gram-negative antibioticsPA Smith, MFT Koehler, HS Girgis, D Yan, Y Chen, Y Chen, JJ Crawford, ...Nature 561 (7722), 189-194, 20182822018
3-) Discovery of a Potent and Selective BCL-XL Inhibitor with in Vivo ActivityZF Tao, L Hasvold, L Wang, X Wang, AM Petros, CH Park, ER Boghaert, ...ACS medicinal chemistry letters 5 (10), 1088-1093, 20142812014
4-) The Erbin PDZ Domain Binds with High Affinity and Specificity to the Carboxyl Termini of δ-Catenin and ARVCF∗RP Laura, AS Witt, HA Held, R Gerstner, K Deshayes, MFT Koehler, ...Journal of Biological Chemistry 277 (15), 12906-12914, 20022082002
5-) Origins of PDZ domain ligand specificity: structure determination and mutagenesis of the Erbin PDZ domainNJ Skelton, MFT Koehler, K Zobel, WL Wong, S Yeh, MT Pisabarro, ...Journal of Biological Chemistry 278 (9), 7645-7654, 20031982003