Miroslav Kašpar

Miroslav Kašpar

Institute of Experimental Medicine - Prague / Czech Republic
Natural Sciences / Chemical Sciences
AD Scientific Index ID: 5249060
Institut experimentálního lékařství
person_outline Miroslav Kašpar's MOST POPULAR ARTICLES
1-) Selectivity of Oxidizing Agents toward Axial and Equatorial Hydroxyl GroupsM Kaspar, E KudovaThe Journal of Organic Chemistry 87 (14), 9157-9170, 202272022
2-) (E)-7-Ethylidene-lithocholic acid (7-ELCA) is a potent dual farnesoid X receptor (FXR) antagonist and GPBAR1 agonist inhibiting FXR-induced gene expression in hepatocytes and …A Stefela, M Kaspar, M Drastik, T Kronenberger, S Micuda, M Dracinsky, ...Frontiers in pharmacology 12, 713149, 202172021
3-) 3β-Isoobeticholic acid efficiently activates the farnesoid X receptor (FXR) due to its epimerization to 3α-epimer by hepatic metabolismA Stefela, M Kaspar, M Drastik, O Holas, M Hroch, T Smutny, J Skoda, ...The Journal of steroid biochemistry and molecular biology 202, 105702, 202062020
4-) When Two Become One: Conformational Changes in FXR/RXR Heterodimers Bound to Steroidal AntagonistsA Díaz‐Holguín, A Rashidian, D Pijnenburg, G Monteiro Ferreira, ...ChemMedChem 18 (4), e202200556, 202332023