Noel Byrne

Noel Byrne

Central US Merck & Co., Inc. - Kenilworth / United States
Natural Sciences / Biological Science
AD Scientific Index ID: 4388528
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person_outline Noel Byrne's MOST POPULAR ARTICLES
1-) Structural basis for the cooperative allosteric activation of the free fatty acid receptor GPR40J Lu, N Byrne, J Wang, G Bricogne, FK Brown, HR Chobanian, SL Colletti, ...Nature structural & molecular biology 24 (7), 570-577, 20171422017
2-) The discovery of fused pyrrole carboxylic acids as novel, potent D-amino acid oxidase (DAO) inhibitorsT Sparey, P Abeywickrema, S Almond, N Brandon, N Byrne, A Campbell, ...Bioorganic & Medicinal Chemistry Letters 18 (11), 3386-3391, 2008972008
3-) Structures of active-state orexin receptor 2 rationalize peptide and small-molecule agonist recognition and receptor activationC Hong, NJ Byrne, B Zamlynny, S Tummala, L Xiao, JM Shipman, ...Nature Communications 12 (1), 815, 2021752021
4-) AX132 PCSK9 antagonistsPP Luo, KC Wangr, P Zhong, M Hsieh, Y Li, X Wang, F Dong, A Golosov, ...US Patent 8,877,900, 2014762014
5-) From screening to targeted degradation: strategies for the discovery and optimization of small molecule ligands for PCSK9WL Petrilli, GC Adam, RS Erdmann, P Abeywickrema, V Agnani, X Ai, ...Cell chemical biology 27 (1), 32-40. e3, 2020742020