Roberto A Chica

Roberto A Chica

Université d'Ottawa - Ottawa / Canada
Natural Sciences / Chemical Sciences
AD Scientific Index ID: 654136
University of Ottawa
person_outline Roberto A Chica's MOST POPULAR ARTICLES
1-) Semi-rational approaches to engineering enzyme activity: combining the benefits of directed evolution and rational designRA Chica, N Doucet, JN PelletierCurrent opinion in biotechnology 16 (4), 378-384, 20056562005
2-) Iterative approach to computational enzyme designHK Privett, G Kiss, TM Lee, R Blomberg, RA Chica, LM Thomas, D Hilvert, ...Proceedings of the National Academy of Sciences 109 (10), 3790-3795, 20123242012
3-) Generation of longer emission wavelength red fluorescent proteins using computationally designed librariesRA Chica, MM Moore, BD Allen, SL MayoProceedings of the National Academy of Sciences 107 (47), 20257-20262, 20101192010
4-) Ensemble-based enzyme design can recapitulate the effects of laboratory directed evolution in silicoA Broom, RV Rakotoharisoa, MC Thompson, N Zarifi, E Nguyen, ...Nature Communications 11 (1), 1-10, 2020101*2020
5-) Rational design of proteins that exchange on functional timescalesJA Davey, AM Damry, NK Goto, RA ChicaNature chemical biology 13 (12), 1280-1285, 2017922017