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Sakshi Tomar
National Cancer Institute - Bethesda / United States
Natural Sciences / Biological Science
AD Scientific Index ID: 4381619
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Sakshi Tomar's MOST POPULAR ARTICLES
1-)
Discovery, Synthesis, And Structure-Based Optimization of a Series of N-(tert-Butyl)-2-(N-arylamido)-2-(pyridin-3-yl) Acetamides (ML188) as Potent Noncovalent …J Jacobs, V Grum-Tokars, Y Zhou, M Turlington, SA Saldanha, P Chase, ...Journal of medicinal chemistry 56 (2), 534-546, 20131662013
2-)
Ligand-induced dimerization of Middle East respiratory syndrome (MERS) coronavirus nsp5 protease (3CLpro): implications for nsp5 regulation and the development of antiviralsS Tomar, ML Johnston, SES John, HL Osswald, PR Nyalapatla, LN Paul, ...Journal of Biological Chemistry 290 (32), 19403-19422, 20151412015
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Chimeric exchange of coronavirus nsp5 proteases (3CLpro) identifies common and divergent regulatory determinants of protease activityCC Stobart, NR Sexton, H Munjal, X Lu, KL Molland, S Tomar, ...Journal of virology 87 (23), 12611-12618, 20131392013
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Discovery of N-(benzo [1, 2, 3] triazol-1-yl)-N-(benzyl) acetamido) phenyl) carboxamides as severe acute respiratory syndrome coronavirus (SARS-CoV) 3CLpro inhibitors …M Turlington, A Chun, S Tomar, A Eggler, V Grum-Tokars, J Jacobs, ...Bioorganic & medicinal chemistry letters 23 (22), 6172-6177, 20131362013
5-)
Targeting zoonotic viruses: Structure-based inhibition of the 3C-like protease from bat coronavirus HKU4—The likely reservoir host to the human coronavirus that causes Middle …SES John, S Tomar, SR Stauffer, AD MesecarBioorganic & medicinal chemistry 23 (17), 6036-6048, 20151032015
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