Sarath Pathuri

Sarath Pathuri

University of Texas Health Science Center at San Antonio - San Antonio / United States
Natural Sciences / Molecular Biology & Genetics
AD Scientific Index ID: 5542707
UT Health San Antonio
person_outline Sarath Pathuri's MOST POPULAR ARTICLES
1-) Discovery of a first-in-class reversible DNMT1-selective inhibitor with improved tolerability and efficacy in acute myeloid leukemiaMB Pappalardi, K Keenan, M Cockerill, WA Kellner, A Stowell, C Sherk, ...Nature cancer 2 (10), 1002-1017, 20211292021
2-) Dual histone methyl reader ZCWPW1 facilitates repair of meiotic double strand breaks in male miceM Mahgoub, J Paiano, M Bruno, W Wu, S Pathuri, X Zhang, S Ralls, ...Elife 9, e53360, 2020382020
3-) Phase II investigation of TVB-2640 (denifanstat) with bevacizumab in patients with first relapse high-grade astrocytomaW Kelly, AE Diaz Duque, J Michalek, B Konkel, L Caflisch, Y Chen, ...Clinical Cancer Research 29 (13), 2419-2425, 2023172023
4-) Structural characterization of dicyanopyridine containing DNMT1-selective, non-nucleoside inhibitorsJR Horton, S Pathuri, K Wong, R Ren, L Rueda, DT Fosbenner, ...Structure 30 (6), 793-802. e5, 2022202022
5-) The highly specific, cell cycle–regulated methyltransferase from Caulobacter crescentus relies on a novel DNA recognition mechanismNO Reich, E Dang, M Kurnik, S Pathuri, CB WoodcockJournal of Biological Chemistry 293 (49), 19038-19046, 2018122018