Severin Lechner

Severin Lechner

Technische Universität München - Munich / Germany
Natural Sciences / Molecular Biology & Genetics
AD Scientific Index ID: 6037527
Technical University of Munich
person_outline Severin Lechner's MOST POPULAR ARTICLES
1-) Target deconvolution of HDAC pharmacopoeia reveals MBLAC2 as common off-targetS Lechner, MIP Malgapo, C Grätz, RR Steimbach, A Baron, P Rüther, ...Nature chemical biology 18 (8), 812-820, 2022652022
2-) Decrypting drug actions and protein modifications by dose-and time-resolved proteomicsJ Zecha, FP Bayer, S Wiechmann, J Woortman, N Berner, J Müller, ...Science 380 (6640), 93-101, 2023432023
3-) Aza-SAHA derivatives are selective histone deacetylase 10 chemical probes that inhibit polyamine deacetylation and phenocopy HDAC10 knockoutRR Steimbach, CJ Herbst-Gervasoni, S Lechner, TM Stewart, G Klinke, ...Journal of the American Chemical Society 144 (41), 18861-18875, 2022202022
4-) Chemoproteomic target deconvolution reveals Histone Deacetylases as targets of (R)-lipoic acidS Lechner, RR Steimbach, L Wang, ML Deline, YC Chang, T Fromme, ...Nature Communications 14 (1), 3548, 2023172023
5-) A region‐resolved proteomic map of the human brain enabled by high‐throughput proteomicsJ Tüshaus, A Sakhteman, S Lechner, M The, E Mucha, C Krisp, J Schlegel, ...The EMBO Journal 42 (23), e114665, 2023142023