Skene R

Skene R

Takeda Pharmaceutical Company Limited - Osaka / Japan
Others
AD Scientific Index ID: 4407058
武田薬品工業株式会社
person_outline Skene R's MOST POPULAR ARTICLES
1-) Structural snapshots of human HDAC8 provide insights into the class I histone deacetylasesJR Somoza, RJ Skene, BA Katz, C Mol, JD Ho, AJ Jennings, C Luong, ...Structure 12 (7), 1325-1334, 20047752004
2-) Structural basis for the autoinhibition and STI-571 inhibition of c-Kit tyrosine kinaseCD Mol, DR Dougan, TR Schneider, RJ Skene, ML Kraus, DN Scheibe, ...Journal of Biological Chemistry 279 (30), 31655-31663, 20047032004
3-) Discovery of alogliptin: a potent, selective, bioavailable, and efficacious inhibitor of dipeptidyl peptidase IVJ Feng, Z Zhang, MB Wallace, JA Stafford, SW Kaldor, DB Kassel, ...Journal of medicinal chemistry 50 (10), 2297-2300, 20074932007
4-) Structural analysis of the mechanism of inhibition and allosteric activation of the kinase domain of HER2 proteinK Aertgeerts, R Skene, J Yano, BC Sang, H Zou, G Snell, A Jennings, ...Journal of Biological Chemistry 286 (21), 18756-18765, 20114072011
5-) Exploration of the HDAC2 foot pocket: Synthesis and SAR of substituted N-(2-aminophenyl)benzamidesJC Bressi, AJ Jennings, R Skene, Y Wu, R Melkus, R De Jong, ...Bioorganic & medicinal chemistry letters 20 (10), 3142-3145, 20103112010