Stefan G Sarafianos

Stefan G Sarafianos

Emory University - Atlanta / United States
Medical and Health Sciences / Pediatrics and Child Health
AD Scientific Index ID: 1371475
person_outline Stefan G Sarafianos's MOST POPULAR ARTICLES
1-) Structure and function of HIV-1 reverse transcriptase: molecular mechanisms of polymerization and inhibitionSG Sarafianos, B Marchand, K Das, DM Himmel, MA Parniak, SH Hughes, ...Journal of molecular biology 385 (3), 693-713, 20096552009
2-) Crystal structure of HIV‐1 reverse transcriptase in complex with a polypurine tract RNA: DNASG Sarafianos, K Das, C Tantillo, AD ClarkJr, J Ding, JM Whitcomb, ...The EMBO journal, 20015332001
3-) Structure and functional implications of the polymerase active site region in a complex of HIV-1 RT with a double-stranded DNA template-primer and an antibody Fab fragment at 2 …J Ding, K Das, Y Hsiou, SG Sarafianos, AD Clark Jr, A Jacobo-Molina, ...Journal of molecular biology 284 (4), 1095-1111, 19984201998
4-) Lamivudine (3TC) resistance in HIV-1 reverse transcriptase involves steric hindrance with β-branched amino acidsSG Sarafianos, K Das, AD Clark Jr, J Ding, PL Boyer, SH Hughes, ...Proceedings of the national academy of sciences 96 (18), 10027-10032, 19993951999
5-) Molecular modeling and biochemical characterization reveal the mechanism of hepatitis B virus polymerase resistance to lamivudine (3TC) and emtricitabine (FTC)K Das, X Xiong, H Yang, CE Westland, CS Gibbs, SG Sarafianos, ...Journal of virology 75 (10), 4771-4779, 20013562001