Takumi Ito

Takumi Ito

Tokyo Medical University - Tokyo / Japan
Natural Sciences / Chemical Sciences
AD Scientific Index ID: 524565
東京医科大学
person_outline Takumi Ito's MOST POPULAR ARTICLES
1-) Identification of a primary target of thalidomide teratogenicity science 327 (5971), 1345-1350, 2010
2-) Cereblon is a direct protein target for immunomodulatory and antiproliferative activities of lenalidomide and pomalidomide Leukemia 26 (11), 2326-2335, 2012
3-) Immunomodulatory agents lenalidomide and pomalidomide co‐stimulate T cells by inducing degradation of T cell repressors I karos and A iolos via modulation of the E 3 ubiquitin … British journal of haematology 164 (6), 811-821, 2014
4-) A novel cereblon modulator recruits GSPT1 to the CRL4CRBN ubiquitin ligase Nature 535 (7611), 252-257, 2016
5-) Structure of the human Cereblon–DDB1–lenalidomide complex reveals basis for responsiveness to thalidomide analogs Nature structural & molecular biology 21 (9), 803-809, 2014