Takumi Ito

Takumi Ito

Tokyo Medical University - Tokyo / Japan
Natural Sciences / Chemical Sciences
AD Scientific Index ID: 524565
東京医科大学
person_outline Takumi Ito's MOST POPULAR ARTICLES
1-) Identification of a primary target of thalidomide teratogenicityT Ito, H Ando, T Suzuki, T Ogura, K Hotta, Y Imamura, Y Yamaguchi, ...science 327 (5971), 1345-1350, 201017232010
2-) Cereblon is a direct protein target for immunomodulatory and antiproliferative activities of lenalidomide and pomalidomideAEA Lopez-Girona, D Mendy, T Ito, K Miller, AK Gandhi, J Kang, ...Leukemia 26 (11), 2326-2335, 20127342012
3-) Immunomodulatory agents lenalidomide and pomalidomide co‐stimulate T cells by inducing degradation of T cell repressors I karos and A iolos via modulation of the E 3 ubiquitin …AK Gandhi, J Kang, CG Havens, T Conklin, Y Ning, L Wu, T Ito, H Ando, ...British journal of haematology 164 (6), 811-821, 20145222014
4-) A novel cereblon modulator recruits GSPT1 to the CRL4CRBN ubiquitin ligaseME Matyskiela, G Lu, T Ito, B Pagarigan, CC Lu, K Miller, W Fang, ...Nature 535 (7611), 252-257, 20165762016
5-) Structure of the human Cereblon–DDB1–lenalidomide complex reveals basis for responsiveness to thalidomide analogsPP Chamberlain, A Lopez-Girona, K Miller, G Carmel, B Pagarigan, ...Nature structural & molecular biology 21 (9), 803-809, 20145552014