Thomas Helleday

Thomas Helleday

University of Sheffield - Sheffield / United Kingdom
Others
AD Scientific Index ID: 1186097
Sheffield University
person_outline Thomas Helleday's MOST POPULAR ARTICLES
1-) Specific killing of BRCA2-deficient tumours with inhibitors of poly (ADP-ribose) polymeraseHE Bryant, N Schultz, HD Thomas, KM Parker, D Flower, E Lopez, S Kyle, ...Nature 434 (7035), 913-917, 200549612005
2-) Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpointsJ Bartkova, N Rezaei, M Liontos, P Karakaidos, D Kletsas, N Issaeva, ...Nature 444 (7119), 633-637, 200621102006
3-) DNA repair pathways as targets for cancer therapyT Helleday, E Petermann, C Lundin, B Hodgson, RA SharmaNature Reviews Cancer 8 (3), 193-204, 200817982008
4-) Mechanisms underlying mutational signatures in human cancersT Helleday, S Eshtad, S Nik-ZainalNature reviews genetics 15 (9), 585-598, 20149852014
5-) The underlying mechanism for the PARP and BRCA synthetic lethality: clearing up the misunderstandingsT HelledayMolecular oncology 5 (4), 387-393, 20119822011