Tim Miles

Tim Miles

GlaxoSmithKline - Needham / United Kingdom
Medical and Health Sciences / Pharmacy & Pharmaceutical Sciences
AD Scientific Index ID: 4371266
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person_outline Tim Miles's MOST POPULAR ARTICLES
1-) Structural basis of quinolone inhibition of type IIA topoisomerases and target-mediated resistanceA Wohlkonig, PF Chan, AP Fosberry, P Homes, J Huang, M Kranz, ...Nature structural & molecular biology 17 (9), 1152-1153, 20102882010
2-) Preclinical candidate for the treatment of visceral leishmaniasis that acts through proteasome inhibitionS Wyllie, S Brand, M Thomas, M De Rycker, C Chung, I Pena, ...Proceedings of the National Academy of Sciences 116 (19), 9318-9323, 20191192019
3-) Cyclin-dependent kinase 12 is a drug target for visceral leishmaniasisS Wyllie, M Thomas, S Patterson, S Crouch, M De Rycker, R Lowe, ...Nature 560 (7717), 192-197, 20181192018
4-) Identification of Trypanocidal Activity for Known Clinical Compounds Using a New Trypanosoma cruzi Hit-Discovery Screening CascadeM De Rycker, J Thomas, J Riley, SJ Brough, TJ Miles, DW GrayPLoS neglected tropical diseases 10 (4), e0004584, 2016772016
5-) Synthesis of highly-functionalised pyridines via hetero-Diels–Alder methodology: reaction of 3-siloxy-1-aza-1, 3-butadienes with electron deficient acetylenesMD Fletcher, TE Hurst, TJ Miles, CJ MoodyTetrahedron 62 (23), 5454-5463, 2006722006