Weiming Xia

Weiming Xia

Boston University - Boston / United States
Others
AD Scientific Index ID: 846958
person_outline Weiming Xia's MOST POPULAR ARTICLES
1-) Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and γ-secretase activityMS Wolfe, W Xia, BL Ostaszewski, TS Diehl, WT Kimberly, DJ SelkoeNature 398 (6727), 513-517, 199924461999
2-) Mutant presenilins of Alzheimer\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\'s disease increase production of 42-residue amyloid β-protein in both transfected cells and transgenic miceM Citron, D Westaway, W Xia, G Carlson, T Diehl, G Levesque, ...Nature medicine 3 (1), 67-72, 199717541997
3-) Skeletal and CNS defects in Presenilin-1-deficient miceJ Shen, RT Bronson, DF Chen, W Xia, DJ Selkoe, S TonegawaCell 89 (4), 629-639, 199711781997
4-) Elevated β-secretase expression and enzymatic activity detected in sporadic Alzheimer diseaseLB Yang, K Lindholm, R Yan, M Citron, W Xia, XL Yang, T Beach, L Sue, ...Nature medicine 9 (1), 3-4, 20039102003
5-) Transition-state analogue inhibitors of γ-secretase bind directly to presenilin-1WP Esler, WT Kimberly, BL Ostaszewski, TS Diehl, CL Moore, JY Tsai, ...Nature cell biology 2 (7), 428-434, 20007562000