Weston Lane

Weston Lane

Takeda Pharmaceutical Company Limited - - / Japan
Natural Sciences / Biological Science
AD Scientific Index ID: 4407602
武田薬品工業株式会社
person_outline Weston Lane's MOST POPULAR ARTICLES
1-) High-resolution structure of the human GPR40 receptor bound to allosteric agonist TAK-875A Srivastava, J Yano, Y Hirozane, G Kefala, F Gruswitz, G Snell, W Lane, ...Nature 513 (7516), 124-127, 20143292014
2-) Crystal structure of human stearoyl–coenzyme A desaturase in complex with substrateH Wang, MG Klein, H Zou, W Lane, G Snell, I Levin, K Li, BC SangNature structural & molecular biology 22 (7), 581-585, 20151362015
3-) Discovery of TAK-981, a first-in-class inhibitor of SUMO-activating enzyme for the treatment of cancerSP Langston, S Grossman, D England, R Afroze, N Bence, D Bowman, ...Journal of medicinal chemistry 64 (5), 2501-2520, 2021702021
4-) Anti‐tumor efficacy of a novel CLK inhibitor via targeting RNA splicing and MYC‐dependent vulnerabilityK Iwai, M Yaguchi, K Nishimura, Y Yamamoto, T Tamura, D Nakata, ...EMBO molecular medicine 10 (6), e8289, 2018842018
5-) Discovery of potent and selective inhibitors of phosphodiesterase 1 for the treatment of cognitive impairment associated with neurodegenerative and neuropsychiatric diseasesP Li, H Zheng, J Zhao, L Zhang, W Yao, H Zhu, JD Beard, K Ida, W Lane, ...Journal of medicinal chemistry 59 (3), 1149-1164, 2016782016