William (Liam) Bonnette

William (Liam) Bonnette

Johnson & Johnson Co. - New Jersey / United States
Medical and Health Sciences / Biochemistry
AD Scientific Index ID: 4384422
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person_outline William (Liam) Bonnette's MOST POPULAR ARTICLES
1-) A DNA hypomethylation signature predicts antitumor activity of LSD1 inhibitors in SCLCHP Mohammad, KN Smitheman, CD Kamat, D Soong, KE Federowicz, ...Cancer cell 28 (1), 57-69, 20154142015
2-) Long-range inhibitor-induced conformational regulation of human IRE1α endoribonuclease activityNO Concha, A Smallwood, W Bonnette, R Totoritis, G Zhang, ...Molecular pharmacology 88 (6), 1011-1023, 2015482015
3-) Structure-based design of a novel SMYD3 inhibitor that bridges the SAM-and MEKK2-binding pocketsGS Van Aller, AP Graves, PA Elkins, WG Bonnette, PJ McDevitt, ...Structure 24 (5), 774-781, 2016472016
4-) A high-throughput dose-response cellular thermal shift assay for rapid screening of drug target engagement in living cells, exemplified using SMYD3 and IDO1DE McNulty, WG Bonnette, H Qi, L Wang, TF Ho, A Waszkiewicz, ...SLAS DISCOVERY: Advancing Life Sciences R&D 23 (1), 34-46, 2018472018
5-) Pharmacologic Characterization of JNJ-42226314,[1-(4-Fluorophenyl) indol-5-yl]-[3-[4-(thiazole-2-carbonyl) piperazin-1-yl] azetidin-1-yl] methanone, a Reversible, Selective …RM Wyatt, I Fraser, N Welty, B Lord, M Wennerholm, S Sutton, ...Journal of Pharmacology and Experimental Therapeutics 372 (3), 339-353, 2020232020