Yimin Qian

Yimin Qian

Accutar Biotechnology, Inc. - / United States
Natural Sciences / Biological Science
AD Scientific Index ID: 4978704
person_outline Yimin Qian's MOST POPULAR ARTICLES
1-) Hijacking the E3 ubiquitin ligase cereblon to efficiently target BRD4 J Lu, Y Qian, M Altieri, H Dong, J Wang, K Raina, J Hines, JD Winkler, ... Chemistry & biology 22 (6), 755-763, 2015 8822015
2-) PROTAC-induced BET protein degradation as a therapy for castration-resistant prostate cancer K Raina, J Lu, Y Qian, M Altieri, D Gordon, AMK Rossi, J Wang, X Chen, ... Proceedings of the National Academy of Sciences 113 (26), 7124-7129, 2016 6012016
3-) The advantages of targeted protein degradation over inhibition: an RTK case studyGM Burslem, BE Smith, AC Lai, S Jaime-Figueroa, DC McQuaid, ...Cell chemical biology 25 (1), 67-77. e3, 20184552018
4-) Ras CAAX peptidomimetic FTI-277 selectively blocks oncogenic Ras signaling by inducing cytoplasmic accumulation of inactive Ras-Raf complexesEC Lerner, Y Qian, MA Blaskovich, RD Fossum, A Vogt, J Sun, AD Cox, ...Journal of Biological Chemistry 270 (45), 26802-26806, 19954671995
5-) Both farnesyltransferase and geranylgeranyltransferase I inhibitors are required for inhibition of oncogenic K-Ras prenylation but each alone is sufficient to suppress human …J Sun, Y Qian, AD Hamilton, SM SebtiOncogene 16 (11), 1467-1473, 19982991998