Yuanyuan Wei

Yuanyuan Wei

Duke-NUS Graduate Medical School Singapore - Singapore / Singapore
Medical and Health Sciences / Microbiology
AD Scientific Index ID: 4456229
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person_outline Yuanyuan Wei's MOST POPULAR ARTICLES
1-) ALS-causing mutations significantly perturb the self-assembly and interaction with nucleic acid of the intrinsically disordered prion-like domain of TDP-43L Lim, Y Wei, Y Lu, J SongPLoS biology 14 (1), e1002338, 20161672016
2-) TDP-43 N terminus encodes a novel ubiquitin-like fold and its unfolded form in equilibrium that can be shifted by binding to ssDNAH Qin, LZ Lim, Y Wei, J SongProceedings of the National Academy of Sciences 111 (52), 18619-18624, 20141132014
3-) TDP-43 NTD can be induced while CTD is significantly enhanced by ssDNA to undergo liquid-liquid phase separationL Wang, J Kang, L Lim, Y Wei, J SongBiochemical and biophysical research communications 499 (2), 189-195, 2018312018
4-) Inter-domain interactions of TDP-43 as decoded by NMRY Wei, L Lim, L Wang, J SongBiochemical and biophysical research communications 473 (2), 614-619, 2016342016
5-) ALS-causing cleavages of TDP-43 abolish its RRM2 structure and unlock CTD for enhanced aggregation and toxicityY Wei, L Lim, L Wang, J SongBiochemical and biophysical research communications 485 (4), 826-831, 2017182017